The Newborn Intensive Care Unit at Brigham and Women’s Hospital in Boston needed our help to answer an important clinical question: does exposure to music reduce stress and improve outcomes for premature babies in the NICU? My team and I took acoustic measurements to understand the baseline sound environment. We pulled in experts in composition and generative music, compiling a randomized and counterbalanced content matrix. And I drew on my deep understanding of usability, acoustics, and retail audio demonstration to design a system that delivers a carefully controlled music exposure with a single button press.